Animations in Life Sciences
Thursday 5 February 2015
Animations in Chemistry (Adobe Flash plugin is required)
Mechanism of the Mannich Reaction
Mechanism of the Strecker Synthesis
Mechanism of the Wittig Reaction
Isocitrate Dehydrogenase
The Class I Aldolase Reaction
Chymotrypsin Mechanism
SOurce http://www.sumanasinc.com/scienceinfocus/scienceinfocus.html
Mechanism of the Mannich Reaction
Mechanism of the Strecker Synthesis
Mechanism of the Wittig Reaction
Isocitrate Dehydrogenase
The Class I Aldolase Reaction
Chymotrypsin Mechanism
SOurce http://www.sumanasinc.com/scienceinfocus/scienceinfocus.html
References Books for CISR Life Sciences
LIFE SCIENCES |
|
Animal Physiology |
Guyton & Hall, Ganong, Moyes & Schulte, Chatterjee & Chatterjee |
Biochemistry |
Lehninger & Lubert stryer, Harper, Voet & Voet, Campbell, Biochemistry of nucleic acid – Adams, Knowler |
Biological Sciences |
Taylor |
Biotechnology |
B. D. Singh, Old Primrose, Click & Pasternak, Brown |
Cell Biology |
Gerald Karp, Bruce Alberts, Cooper & Hansman, De Robertis, Lordish & Baltimore |
Development Biology |
S. F. Gilbert |
Ecology |
P. D. Sharma, E. P. Odum, M. C. Dash, Kormondy |
Environmental Biology & Biodiversity |
Odum & Barret, Townsend & Harper, Smith & Smith, P. D. Sharma |
Evolution |
V.B.Rastogi, Veer bala |
Gene Cloning & DNA Analysis |
T. A. Brown |
Genetics |
Griffith , Gardner, Clug & Cummins, Lewin, Strickberger, Simmons & Snustad, |
Genome analysis |
Old and Primrose |
Immunology |
Kuby |
Medical Biochemistry |
Harper |
Microbiology |
Prescott & Harley, Madigan & Martinko, Pelczar |
Molecular biology |
Genes VIII, Voet & Voet, Baltimore, Lodish, Lehninger, Freifelder |
Plant physiology |
Taiz & Zeiger, William J. Hopkins, Salisbury & Ross, Devlin & Withan |
Plant Tissue Culture |
Bhojwani & Razdan |
Principles of Gene Manipulation & Genomics |
Primrose & Twyman |
Recombinant DNA |
Watson, Candy, Myers & Witkowski |
Taxonomy |
Subramanyam, Naik |
Technique Biophysical |
David Sheehan |
Techniques |
Wilson & N.Walker, Wilson & Goulding Upadhyay & Nath, David Freifelder |
CHEMISTRY |
|
1. Physical Chemistry |
(i) P.W. Atkins (ii) Puri, Sharma & Pathania (iii) K. L. Kapoor Vol. I to IV (iv) Barrow & Levine (v) Group Theory- F.A. Cotton (vi) Quantum Chemistry- Levine or R K Parsad |
2. Inorganic Chemistry |
(i) J. D. Lee (ii) Huheey (iii) Madan, Malik & Tuli –Selected topics (iv) Puri, Sharma, Kalia (v) Wilkinson & Cotton –Advanced Inorganic Chemistry |
3. Organic Chemistry |
(i) Claydden, Greeves, Warren, Worthers & Jerry March (ii) Carrey- Advanced organic Chemistry (iii) Morrison & Boyd (iv) Jagdamba Singh –Pericyclic reaction (v) Mukherjee & Singh –Reaction Mechanism (vi) Sanyal & Sanyal –Reactions, Reaarangements & Reagents (vii) Silver Stein,Y.R. Sharma –Spectroscopy (viii) P.S.Kalsi- Spectroscopy, Stereo chemistry (ix) Banwell- Spectroscopy (x) Coxon & Halton- Photo chemistry (xi) I. L. Finar Vol I & II |
PHYSICS
Atomic & Molecular Spectra |
Raj kumar,White |
Classical Mechanics |
Goldstein/J.C.Upadhyay Central forces – Goldstein Small Oscillation – Goldstein R.B.D. – Landon |
Electromagnetic Theory |
D.Griffiths/Satya Prakash/Chopra & Agrawal |
Electronics |
Millmann &Halkias/B.L.Thareja vol.4., Millmann &Grabell, Malvino, For Digital Electronics – Malvin & Leech |
Mathematical Physics |
Matrices – A.W.Joshi Complex variables – Schaum Series Vector calculation – Schaum Series Linear D.E. and other function –Shankara Rao/Any graduation book Miscellaneous: Arfkin/ Erwin Kreyszig / B.S.Grewal. |
Atomic & Molecular Spectra |
Banwell & Mc Cash, Raj Kumar |
Nuclear & Particle Physics |
D.C.Tayal, For Nuclear- Cohen, S.P.Patel For Particle-Griffith |
Quantum Mechanics |
Bransden & Joachain/H.C.Verma /Satya Prakash Cohen Tannudji or by Griffith |
Solid state Physics |
Kietal, Aschroft & Mermin, Decker |
Thermodynamics & Statistical Physics |
Sears & Salinger/Garg, Bansal & Ghosh/P. K. Chakraborty, F.Rief, Patharia |
MATHEMATICS
Modern Algebra |
A.R.Vasistha,I.N.Herstein, Khanna & S.K.Bhambri, R.Kumar, Gallian, Artin |
Complex Analysis |
Schaum Series, Kasana J.N.Sharma & A.R.Vasistha, Churchil,J.B. Conway |
Linear Algebra |
Schaum Series, G.Hadley & A.R.Vasistha, Hoffman & Kunze |
Matrices |
A.R.Vasistha, Schaum |
Operation Research |
S.D. Sharma, Kanti Swaroop, H.A.Taha, G.J.Lieberman |
Differential Equation |
Gupta & Kapoor, Schaum Series, Gun, Gupta&Dasgupta, Part I &II |
Discrete Mathematics |
Kolman, Busby & Ross, Trembly – Manohar, V.K. Balakrishan |
Number Theory |
Zuckerman, Burton |
Numerical Analysis |
S.S.Shastry, Jain, Lyenger & Jain, Erwin Kreyszig |
Integral Transform |
Krishna series, Erwin Kreyszig |
Higher Engineering Mathematics |
B.S.Grewal / Erwin Kreyszig |
Differential Geometry |
Krishna series |
Integral Equation |
Krishna series, M.D.Raisinghania |
Topology |
Krishna series, Simmons, J.N. Sharma, MUNKRES |
Functional Analysis |
Krishna series, Vasishtha & Sharma |
Mechanics |
Krishna series,Gupta &Gupta |
Real Analysis |
A.R.Vasistha, Arora & Malik, N.P.Bali, Apostol, W.Rudin, R.R.Goldbarg, Asha Rani Singhal |
Mathematical Analysis |
Arora & Malik, N.P.Bali, Rudin, Vasishtha, S.Bartle |
Calculus of variation |
M.D.Raisinghania,Silverman, Rober |
ODE- |
Erwin Kreyszig, Simmons |
PDE- |
Ian –Snedon, T.Amarnath |
About gate
The Graduate Aptitude Test in Engineering (GATE), is an All-India Examination conducted by the seven Indian Institutes of Technology and the Indian Institute of Science, Banglore, on behalf of the National Coordinating Board – GATE, Department of Education, Ministry of Human Resources Development (MHRD), Government of India.
Objective of GATE
The objective of GATE is to identify meritorious and motivated candidates for admission in Postgraduate Programs in Engineering at the national level. Some Engineering Colleges/Institutes specify GATE as a mandatory qualification for admission for Postgraduate Programs. For doing M.Tech. and Ph.D programme from IIT, IISc and other reputed institutes one should have GATE score. The GATE qualified students are given their all India Rank (also percentile). On the basis of this score students have to applied for different IITs or other insitutes.Eligibility
The following categories of candidates are eligible to appear in GATE:
1. Bachelor degree holders in Engineering/ Technology/ Architecture (4 years after 10+2) and those who are in the final or pre-final year of such programmes.2. Master degree holders in any branch of Science/ Mathematics/ Statistics/ Computer Applications or equivalent and those who are in the final or pre-final year of such programmes.
3. Candidates in the second or higher year of the Four-year Integrated Master degree programme (Post-B.Sc.) in Engineering/ Technology or in the third or higher year of Five-year Integrated Master degree programme and Dual Degree programme in Engineering/ Technology.
4. Candidates with qualifications obtained through examinations conducted by professional societies recognised by UPSC/AICTE (e.g. AMIE by IE(I), AMICE(I) by the Institute of Civil Engineers (India)-ICE(I)) as equivalent to B.E./B.Tech. Those who have completed section A or equivalent of such professional courses are also eligible.
Examination structure
The GATE examination consists of a single paper of 3 hours duration, which contains 65 questions carrying a maximum of 100 marks. The question paper will consist of only multiple choice objective questions. Each question will have four choices for the answer. The candidates will have to mark the correct choice on an Optical Response Sheet (ORS) by darkening the appropriate bubble against each question. There will be negative marking for each wrong answer, as explained in Question Paper Pattern.Chemistry SYLLABUS
Council of Scientific and Industrial Research
Human Resource Development Group
CHEMICAL SCIENCES
EXAM SCHEME
TIME: 3 HOURS MAXIMUM MARKS: 200
From June, 2011 CSIR- Exam for Award of Junior Research Fellowship shall be a Single Paper Test having Multiple Choice Questions (MCQs). The question paper is divided in three parts
Part ‘A’
This part shall carry 20 questions pertaining to General Science, Quantitative Reasoning & Analysis and Research Aptitude. The candidates shall be required to answer any 15 questions. Each question shall be of two marks. The total marks allocated to this section shall be 30 out of 200.
Part ‘B’
This part shall contain 50 Multiple Choice Questions(MCQs) generally covering the topics given in the syllabus. A candidate shall be required to answer any 35 questions. Each question shall be of two marks. The total marks allocated to this section shall be 70 out of 200.
Part ‘C’
This part shall contain 75 questions that are designed to test a candidate’s knowledge of scientific concepts and/or application of the scientific concepts. The questions shall be of analytical nature where a candidate is expected to apply the scientific knowledge to arrive at the solution to the given scientific problem. A candidate shall be required to answer any 25 questions. Each question shall be of four marks. The total marks allocated to this section shall be 100 out of 200.
� There will be negative marking @25% for each wrong answer. (not confirm)
� To enable the candidates to go through the questions, the question paper booklet shall be distributed 15 minutes before the scheduled time of the exam. The Answer sheet shall be distributed at the scheduled time of the exam.
� On completion of the exam i.e. at the scheduled closing time of the exam, the candidates shall be allowed to carry the Question Paper Booklet. No candidate is allowed to carry the Question Paper Booklet in case he/she chooses to leave the test before the scheduled closing time.
Inorganic Chemistry
1. Chemical periodicity
2. Structure and bonding in homo- and heteronuclear molecules, including shapes of molecules (VSEPR Theory).
3. Concepts of acids and bases, Hard-Soft acid base concept, Non-aqueous solvents.
4. Main group elements and their compounds: Allotropy, synthesis, structure and bonding, industrial importance of the compounds.
5. Transition elements and coordination compounds: structure, bonding theories, spectral and magnetic properties, reaction mechanisms.
6. Inner transition elements: spectral and magnetic properties, redox chemistry, analytical applications.
7. Organometallic compounds: synthesis, bonding and structure, and reactivity. Organometallics in homogeneous catalysis.
8. Cages and metal clusters.
9. Analytical chemistry- separation, spectroscopic, electro- and thermoanalytical methods.
10. Bioinorganic chemistry: photosystems, porphyrins, metalloenzymes, oxygen transport, electron- transfer reactions; nitrogen fixation, metal complexes in medicine.
11. Characterisation of inorganic compounds by IR, Raman, NMR, EPR, M�ssbauer, UV-vis, NQR, MS, electron spectroscopy and microscopic techniques.
12. Nuclear chemistry: nuclear reactions, fission and fusion, radio-analytical techniques and activation analysis.
Physical Chemistry:
1. Basic principles of quantum mechanics: Postulates; operator algebra; exactly-
solvable systems: particle-in-a-box, harmonic oscillator and the hydrogen atom, including shapes of atomic orbitals; orbital and spin angular momenta; tunneling.
2. Approximate methods of quantum mechanics: Variational principle; perturbation theory up to second order in energy; applications.
3. Atomic structure and spectroscopy; term symbols; many-electron systems and antisymmetry principle.
4. Chemical bonding in diatomics; elementary concepts of MO and VB theories; Huckel theory for conjugated p-electron systems.
5. Chemical applications of group theory; symmetry elements; point groups; character tables; selection rules.
6. Molecular spectroscopy: Rotational and vibrational spectra of diatomic molecules; electronic spectra; IR and Raman activities � selection rules; basic principles of magnetic resonance.
7. Chemical thermodynamics: Laws, state and path functions and their applications; thermodynamic description of various types of processes; Maxwell’s relations; spontaneity and equilibria; temperature and pressure dependence of thermodynamic quantities; Le Chatelier principle; elementary description of phase transitions; phase equilibria and phase rule; thermodynamics of ideal and non-ideal gases, and solutions.
8. Statistical thermodynamics: Boltzmann distribution; kinetic theory of gases; partition functions and their relation to thermodynamic quantities � calculations for model systems.
9. Electrochemistry: Nernst equation, redox systems, electrochemical cells; Debye-Huckel theory; electrolytic conductance � Kohlrausch’s law and its applications; ionic equilibria; conductometric and potentiometric titrations.
10. Chemical kinetics: Empirical rate laws and temperature dependence; complex reactions; steady state approximation; determination of reaction mechanisms; collision and transition state theories of rate constants; unimolecular reactions; enzyme kinetics; salt effects; homogeneous catalysis; photochemical reactions.
11. Colloids and surfaces: Stability and properties of colloids; isotherms and surface area; heterogeneous catalysis.
12. Solid state: Crystal structures; Bragg’s law and applications; band structure of solids.
13. Polymer chemistry: Molar masses; kinetics of polymerization.
14. Data analysis: Mean and standard deviation; absolute and relative errors; linear regression; covariance and correlation coefficient.
Organic Chemistry
1. IUPAC nomenclature of organic molecules including regio- and stereoisomers.
2. Principles of stereochemistry: Configurational and conformational isomerism in acyclic and cyclic compounds; stereogenicity, stereoselectivity, enantioselectivity, diastereoselectivity and asymmetric induction.
3. Aromaticity: Benzenoid and non-benzenoid compounds � generation and reactions.
4. Organic reactive intermediates: Generation, stability and reactivity of carbocations, carbanions, free radicals, carbenes, benzynes and nitrenes.
5. Organic reaction mechanisms involving addition, elimination and substitution reactions with electrophilic, nucleophilic or radical species. Determination of reaction pathways.
6. Common named reactions and rearrangements � applications in organic synthesis.
7. Organic transformations and reagents: Functional group interconversion including oxidations and reductions; common catalysts and reagents (organic, inorganic, organometallic and enzymatic). Chemo, regio and stereoselective transformations.
8. Concepts in organic synthesis: Retrosynthesis, disconnection, synthons, linear and convergent synthesis, umpolung of reactivity and protecting groups.
9. Asymmetric synthesis: Chiral auxiliaries, methods of asymmetric induction � substrate, reagent and catalyst controlled reactions; determination of enantiomeric and diastereomeric excess; enantio-discrimination. Resolution � optical and kinetic.
10. Pericyclic reactions � electrocyclisation, cycloaddition, sigmatropic rearrangements and other related concerted reactions. Principles and applications of photochemical reactions in organic chemistry.
11. Synthesis and reactivity of common heterocyclic compounds containing one or two heteroatoms (O, N, S).
12. Chemistry of natural products: Carbohydrates, proteins and peptides, fatty acids, nucleic acids, terpenes, steroids and alkaloids. Biogenesis of terpenoids and alkaloids.
13. Structure determination of organic compounds by IR, UV-Vis, 1H & 13C NMR and Mass spectroscopic techniques.
Interdisciplinary topics
1. Chemistry in nanoscience and technology.
2. Catalysis and green chemistry.
3. Medicinal chemistry.
4. Supramolecular chemistry.
5. Environmental chemistry.
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